Computational Genomics & NGS

NGS Data Analysis

AI-Powered Next-Generation Sequencing (NGS) Data Analysis for Genomics, Transcriptomics & Precision Medicine

NGS Data Analysis

RASA Life Science Informatics provides comprehensive NGS Data Analysis Services for pharmaceutical companies, biotechnology organizations, hospitals, CROs, research institutes, and academic laboratories. Our bioinformatics experts deliver scalable, cloud-ready, and AI-assisted genomics workflows that transform raw sequencing data into actionable biological insights.

We support all major sequencing applications, including RNA-Seq, Whole Genome Sequencing (WGS), Whole Exome Sequencing (WES), Single-Cell Omics, Spatial Transcriptomics, Metagenomics, Epigenomics, Long-Read Sequencing, Multi-Omics Integration, Clinical Genomics, and Biomarker Discovery.

Using industry-standard bioinformatics tools and reproducible computational pipelines, we help researchers accelerate biomarker discovery, disease mechanism studies, precision medicine initiatives, drug discovery programs, and translational research.

Service Offerings

NGS Analysis Services We Offer

Transcriptomics (RNA-Seq)

Gene expression analysis, differential expression, pathway enrichment, fusion detection, and transcriptomics interpretation.

  • โœ“Gene expression analysis
  • โœ“Differential expression
  • โœ“Pathway enrichment
  • โœ“Fusion detection
  • โœ“Transcriptomics interpretation

Technologies & Pipelines

STAR DESeq2 Salmon edgeR FASTQC MultiQC
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Single-Cell Omics

Single-cell RNA-Seq, scATAC-Seq, cell type annotation, trajectory analysis, and cellular heterogeneity studies.

  • โœ“Single-cell RNA-Seq
  • โœ“scATAC-Seq profiling
  • โœ“Cell type annotation
  • โœ“Trajectory analysis
  • โœ“Cellular heterogeneity studies

Technologies & Pipelines

Seurat Scanpy Cell Ranger 10x Chromium SMART-seq2
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Whole Genome & Whole Exome Sequencing

Variant calling, annotation, structural variant detection, CNV analysis, and rare disease genomics.

  • โœ“Variant calling & annotation
  • โœ“Structural variant detection
  • โœ“Copy Number Variation (CNV)
  • โœ“Rare disease genomics

Technologies & Pipelines

GATK DeepVariant bcftools ANNOVAR Illumina
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Spatial Transcriptomics

Spatial gene expression profiling, tissue architecture analysis, and cellโ€“cell interaction studies.

  • โœ“Spatial gene expression profiling
  • โœ“Tissue architecture analysis
  • โœ“Cellโ€“cell interaction studies

Technologies & Pipelines

Seurat Giotto Squidpy 10x Visium CosMx SMI
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Metagenomics & Microbiome

Taxonomic profiling, functional analysis, microbial diversity assessment, and hostโ€“microbiome interactions.

  • โœ“Taxonomic profiling
  • โœ“Functional analysis
  • โœ“Microbial diversity assessment
  • โœ“Hostโ€“microbiome interactions

Technologies & Pipelines

QIIME2 Kraken2 Humann3 MetaPhlAn Mothur
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Epigenomics

ATAC-Seq, ChIP-Seq, DNA methylation analysis, chromatin accessibility, and regulatory genomics.

  • โœ“ATAC-Seq & ChIP-Seq
  • โœ“DNA methylation analysis
  • โœ“Chromatin accessibility
  • โœ“Regulatory genomics

Technologies & Pipelines

MACS2 Bismark MEME Suite HOMER DiffBind
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Long-Read Sequencing

Oxford Nanopore and PacBio HiFi analysis, isoform discovery, structural variants, and genome assembly.

  • โœ“Oxford Nanopore analysis
  • โœ“PacBio HiFi & Iso-Seq
  • โœ“Isoform discovery
  • โœ“Structural variant detection
  • โœ“Genome assembly

Technologies & Pipelines

Flye Minimap2 Sniffles Canu ONT / PacBio
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Multi-Omics Integration

Integration of genomics, transcriptomics, proteomics, and metabolomics for systems-level biological insights.

  • โœ“Genomics & Transcriptomics integration
  • โœ“Proteomics & Metabolomics integration
  • โœ“Systems-level biological insights

Technologies & Pipelines

mixOmics MOFA2 WGCNA Cytoscape R / Python
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Clinical Genomics

Cancer genomics, rare disease analysis, variant interpretation, and precision medicine applications.

  • โœ“Cancer genomics
  • โœ“Rare disease analysis
  • โœ“Variant interpretation
  • โœ“Precision medicine applications

Technologies & Pipelines

ClinVar dbSNP VEP GATK-MuTect2 SnpEff
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Biomarker Discovery

Identification of diagnostic, prognostic, predictive, and therapeutic biomarkers.

  • โœ“Diagnostic biomarkers
  • โœ“Prognostic biomarkers
  • โœ“Predictive biomarkers
  • โœ“Therapeutic biomarkers

Technologies & Pipelines

Scikit-Learn XGBoost DESeq2 Bioconductor R / ML
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Technology

Technologies & Platforms

Sequence Analysis

FASTQC
MultiQC
BWA
STAR
HISAT2

Variant Analysis

GATK
DeepVariant
bcftools
ANNOVAR

Single-Cell Analysis

Cell Ranger
Seurat
Scanpy

Multi-Omics & Statistics

R
Python
Bioconductor

Workflow Management

Nextflow
Snakemake
Docker
Singularity
Deliverables

Deliverables

โœ“Quality Control Reports
โœ“Differential Expression Analysis
โœ“Variant Annotation Reports
โœ“UMAP & Clustering Visualizations
โœ“Pathway Enrichment Analysis
โœ“Biomarker Discovery Reports
โœ“Publication-Ready Figures
โœ“Interactive Dashboards
โœ“Comprehensive Scientific Reports
Sectors

Industries We Serve

Biopharma & Therapeutics

Accelerate target validation, biomarker discovery, and safety genomics to support biopharmaceutical drug discovery pipelines.

Clinical Diagnostics & CROs

Support clinical trials and translation workflows with rare disease screening, cancer panels, and clinical variant interpretation.

Academic & Research Institutes

Collaborate with university and government labs to deliver publication-ready bioinformatics data and figures for research grants.

AgriGenomics & Plant Breeding

Power crop improvement, marker-assisted selection, host-pathogen transcriptomics, and plant health optimization projects.

Microbiome & Meta-Genomics

Analyze taxonomic profiling, soil pathobiome monitoring, and human/animal host-microbiome interactions.

AI & Translational Biology

Integrate multi-omics datasets with machine learning models for predictive genomics and precision medicine applications.

Why RASA

Why Choose RASA?

AI-Assisted Bioinformatics

Machine learning-enabled workflows for biomarker discovery, variant prioritization, and predictive genomics.

Multi-Platform Expertise

Support for Illumina, Oxford Nanopore, PacBio HiFi, and 10x Genomics platforms.

End-to-End Analysis

From raw sequencing data to biological interpretation and publication-ready reports.

Cloud-Ready Infrastructure

Deployable on AWS, Google Cloud, HPC clusters, and secure on-premise environments.

Reproducible Workflows

Built using Nextflow, Snakemake, Docker, and Singularity for enterprise-grade bioinformatics operations.

Service FAQ

Frequently Asked Questions

RASA Life Science Informatics provides comprehensive Computational Genomics services designed to transform complex sequencing and multi-omics datasets into actionable biological insights. Our expertise includes RNA-Seq analysis, Single-Cell Omics, Whole Genome Sequencing (WGS), Whole Exome Sequencing (WES), Spatial Transcriptomics, Metagenomics & Microbiome Analysis, Epigenomics, Long-Read Sequencing, Multi-Omics Integration, Clinical Genomics, and Biomarker Discovery. These services support pharmaceutical research, biotechnology innovation, clinical genomics, precision medicine, and translational research programs.

Computational Genomics combines genomics, bioinformatics, statistics, machine learning, and computational biology to analyze and interpret large-scale biological datasets. It enables researchers to identify disease-associated genes, discover biomarkers, understand molecular pathways, characterize cellular populations, and support precision medicine initiatives. Computational genomics plays a critical role in modern drug discovery, clinical research, cancer genomics, rare disease studies, and personalized healthcare.

Our bioinformatics workflows support data generated from leading sequencing and omics platforms, including:
Illumina Sequencing
Oxford Nanopore Technologies (ONT)
PacBio HiFi & Iso-Seq
10x Genomics Chromium
NanoString GeoMx DSP
CosMx SMI
MERFISH
Slide-seq
SMART-seq2
Parse Biosciences
We continuously adapt our pipelines to support emerging genomics and spatial omics technologies.

Yes. We provide complete end-to-end bioinformatics analysis starting from raw FASTQ files. Our workflows include quality control, adapter trimming, sequence alignment, transcript quantification, variant calling, statistical analysis, pathway enrichment, biological interpretation, and publication-ready reporting. We also support BAM, CRAM, VCF, count matrices, expression tables, and processed sequencing datasets.

Our NGS and Computational Genomics services include:
Transcriptomics (RNA-Seq)
Single-Cell Omics
Whole Genome Sequencing (WGS)
Whole Exome Sequencing (WES)
Spatial Transcriptomics
Metagenomics & Microbiome Analysis
Epigenomics (ATAC-Seq, ChIP-Seq, DNA Methylation)
Long-Read Sequencing Analysis
Multi-Omics Integration
Clinical Genomics
Biomarker Discovery
Each workflow is customized to the biological question, sequencing platform, and project objectives.

Yes. We develop customized bioinformatics workflows based on:
Organism type
Sequencing technology
Experimental design
Research objectives
Clinical applications
Regulatory requirements
Data volume and infrastructure requirements
Our pipelines are designed to be reproducible, scalable, and suitable for both academic research and industry projects.

We support genomics projects across a wide range of organisms and sample types, including:
Human samples
Animal models
Plant genomics
Microbial genomes
Environmental samples
Cancer tissues
Clinical specimens
Single-cell datasets
Metagenomic communities
Our workflows can be adapted for both model and non-model organisms.

Yes. We specialize in integrating multiple biological data types, including genomics, transcriptomics, epigenomics, proteomics, metabolomics, and clinical datasets. Multi-omics integration helps uncover complex biological mechanisms, identify biomarkers, prioritize therapeutic targets, and support precision medicine research.

Absolutely. Computational genomics is widely used for:
Therapeutic target identification
Biomarker discovery
Disease pathway analysis
Precision medicine research
Drug response prediction
Patient stratification
Translational medicine programs
These insights help accelerate drug discovery and clinical development programs.

Project deliverables typically include:
Quality Control Reports
Statistical Analysis Reports
Differential Expression Analysis
Variant Calling Results
Pathway Enrichment Analysis
Network Biology Analysis
Biomarker Discovery Reports
Interactive Visualizations
Publication-Ready Figures
Comprehensive Scientific Reports
Deliverables can be customized according to project requirements.

Yes. All projects include high-quality scientific visualizations, biological interpretation, methodology documentation, and publication-ready figures suitable for journal manuscripts, grant applications, regulatory submissions, and presentations.

Depending on project requirements, we utilize industry-standard tools including:
FASTQC
MultiQC
STAR
HISAT2
Salmon
GATK
DeepVariant
Seurat
Scanpy
Cell Ranger
QIIME2
Kraken2
Bismark
MACS2
Cytoscape
DESeq2
edgeR
Our workflows are continuously updated to incorporate the latest bioinformatics methodologies.

Yes. Our bioinformatics workflows are deployable on:
Amazon Web Services (AWS)
Google Cloud Platform (GCP)
Microsoft Azure
High-Performance Computing (HPC) Clusters
On-Premise Servers
We use technologies such as Nextflow, Snakemake, Docker, and Singularity to ensure reproducibility and scalability.

We maintain strict confidentiality and data security standards. Client data is handled through secure storage, encrypted transfers, controlled access policies, and optional Non-Disclosure Agreements (NDAs). We follow best practices for data protection and project confidentiality throughout the engagement.

RASA combines expertise in genomics, bioinformatics, computational biology, and AI-driven analytics to deliver scalable, scientifically rigorous, and reproducible solutions. Our team supports pharmaceutical companies, biotechnology organizations, hospitals, CROs, and academic researchers through customized workflows, advanced analytical capabilities, publication-ready reporting, and collaborative scientific support.

Getting started is simple. Share your project objectives, study design, and available datasets with our team. We will assess your requirements, recommend the most suitable analytical workflow, provide a project proposal, and deliver a customized solution tailored to your research or business goals.
๐Ÿ“ง info@rasalifesciences.com
๐ŸŒ www.rasalifesciences.com

Ready to partner with a trusted bioinformatics company in India?

Get in touch with our team in Pune, India to discuss sample sizes, platform details, and custom bioinformatics pipeline configurations for your research program.

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