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Bioinformatics & In-Silico Discovery

Computational precision for molecular discovery.

RASA Life Science Informatics delivers AI-powered NGS data analysis services IndiaHigh-throughput DNA and RNA sequencing workflows. and in-silico drug discovery, transforming raw sequence data into therapeutic insights for pharmaceutical, biotechnology, and clinical R&D.

High-Throughput Genomics

Automated NGS pipeline development at scale.

Process whole-exome (WES), whole-genome (WGS), and RNA-seq datasets. Secure, containerized pipelines (Nextflow, Snakemake) deployable on AWS Batch spot instances.

DNA Sequencing Flow Diagram
Structure-Based Drug Design

Accelerate target validation and virtual screening.

Leverage AlphaFold2 structural models, GPU-accelerated molecular docking, and GROMACS molecular dynamics simulations to optimize leads and filter toxicity.

Molecular Docking
High-Resolution Tissue Architecture

Map cellular transcriptomics in spatial context.

Resolve cellular heterogeneity and tumor microenvironments using 10x Genomics Visium, Slide-seq, and MERFISH data analytics pipelines.

Spatial Cell Mapping
Microbial Community Profiling

Deconvolve complex microbial populations.

Analyze taxonomic composition and functional pathways from gut microbiome sequencing. Shotgun metagenomics pipelines (Kraken2, HUMAnN3).

Metagenomics & Microbiome Analysis
Validated R&D Success

Proven biological insights for clinical success.

Discover how our PhD-level computational biologists helped validate novel CD8+ T-cell exhausted targets, saving 65% in target validation costs.

Validated R&D Success
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RNA-seq samples analyzed
Multi-TB
Genomics datasets processed
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Reproducible pipelines
AI-Native
Workflow architecture
Capability Spectrum

Specialized R&D solutions, built for biotech & pharma.

Metagenomics
★ 4.9 (24 Projects) QIIME2 / Shotgun 3 Wks

Metagenomics

Characterize microbial communities using 16S rRNA and shotgun metagenomics for taxonomic profiling, functional annotation, and pathway reconstruction.

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Multigenomics
★ 5.0 (19 Projects) MOFA+ / SNF 4-6 Wks

Multigenomics

Integrate genomic, transcriptomic, epigenomic, and proteomic datasets using advanced machine learning models to identify key regulatory networks.

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Clinical Genomics
★ 4.9 (15 Projects) ACMG / ClinVar 2 Wks

Clinical Genomics

ACMG-guided variant interpretation, tertiary clinical reporting, and diagnostics pipelines for inherited disorders and rare genetic diseases.

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Biomarker Discovery
★ 4.8 (21 Projects) ML / LASSO 3 Wks

Biomarker Discovery

Statistical and machine learning workflows to identify robust genomic, transcriptomic, and clinical biomarkers for patient stratification.

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Molecular Dynamics
★ 5.0 (22 Projects) GROMACS / Amber 4 Wks

Molecular Dynamics

Simulate macromolecular motion, binding pathways, and conformational stability to calculate binding free energy and validate ligand interactions.

Explore MD
Virtual Screen Docking
★ 4.9 (27 Projects) AutoDock Vina 3 Wks

Virtual Screen Docking

High-throughput structure-based virtual screening and shape-based pharmacophore docking of commercial compound databases against targets.

Explore Docking
Protein Structure Modelling
★ 4.8 (18 Projects) Modeller / PyMOL 2 Wks

Protein Structure Modelling

High-accuracy homology modeling, loop refinement, and structural validation of uncharacterized protein targets to accelerate drug discovery.

Explore Modeling
AI & De Novo Drug Design
★ 5.0 (14 Projects) Generative AI 4 Wks

AI & De Novo Drug Design

Utilize deep generative chemistry models (GENTRL, REINFORCE) to design novel, synthetically feasible small molecules with target binding profiles.

Explore De Novo
Core Workflow

From raw FASTQ sequencing reads to validated insights.

Our containerized, reproducible bioinformatics workflows ensure that raw sequencing datasets are quality controlled, mapped, and mathematically modeled with full scientific rigor.

01
Ingestion & Quality Inspection
Adapter removal, fastp trimming, and automated multi-sample quality control reporting via MultiQC.
02
Alignment & Expression Counting
Ultra-fast genomic mapping using STARSpliced Transcripts Alignment to a Reference - high speed RNA-seq aligner., HISAT2, or de novo transcripts quantification using Salmon.
03
Signal Modeling & Statistics
Differential expression modeling (DESeq2), cell clustering (Seurat/Scanpy), or variant detection (GATK4).
04
Reporting & Visual Dashboards
Clean, publication-ready figures, annotated tables, interactive browser dashboards, and Nextflow pipeline logs.
Operational Execution System

Our Signature Workflow

A structured, client-centric methodology guiding every engagement from initial scoping through to final research delivery.

Client challenge

  • Understanding problem statement
  • Scoping strategic requirements

Solution strategy

  • Defining scientific approach
  • Suitable to client environment

Client approval

  • Client-approved solution strategy
  • Client-approved business model

Go-live on project

  • Dedicated resources
  • Defined project structure & outline
Computational biologists Subject matter experts Data Scientists R&D IT resources

Project updates

  • Client review & feedback
  • Frequent touchpoints

Output and delivery

  • Milestones & final deliverables
  • Reports, dashboards, hypothesis

Interfaced with industry-standard sequencing & cloud systems

Illumina NovaSeq Oxford Nanopore PromethION PacBio Revio 10x Genomics Visium Nextflow Workflows Amazon Web Services
Start Your Project

Looking for a leading bioinformatics company in India?

RASA provides secure, cloud-scale computational genomics and drug design solutions. Talk to our bioinformatics experts in Pune today to discuss your data analysis requirements.

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